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Clinical Trials for Inhalable Measles Vaccine to Begin in India Next Year
The researcher said that the weakened measles virus is mixed with "supercritical" carbon dioxide - part gas, part liquid - to produce microscopic bubbles and droplets, which then are dried to make an inhalable powder.
The powder is puffed into a small, cylindrical, plastic sack, with an opening like the neck of a plastic water bottle, and administered.
"By taking one deep breath from the sack, a child could be effectively vaccinated," Sievers said.
He says that, in animal tests, the inhaler has been found to be just as effective in delivering measles vaccine as the traditional injection.
The researchers are now working on an inexpensive dry powder inhaler that would deliver measles or influenza vaccines to developing nations, and could be used elsewhere.
They believe that the new method may also do away with the problem of people refusing inoculations because of their fear of needles.
Sievers says if the inhaler passes final safety and effectiveness tests, the Serum Institute of India Ltd. expects a demand growing to 400 million doses of measles vaccine a year.
"Human clinical trials are expected to begin next year in India, after animal safety studies are completed this year.
About two-thirds of the world's deaths due to measles occur in that nation. Worldwide, several hundred people die every day from measles-related disease," he said.
Source-ANI
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More News on: Measles , Clinical Trials, Clinical Trials - The Past and The Future , Clinical Trials - Different Phases of the trial , Placebo Effects: Rare Insights, Vaccination for Children
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