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Circulating Tumour Cells may Help to Detect the Recurrence of Breast Cancer
Addressing a press conference at the European Cancer Conference (ECCO 14) on Monday, Dr. Julia Juckstock said that the results could help improve the design of trials of chemotherapy in breast cancer, and reduce costs to health services.
Led by Dr. Brigitte Rack, the research team analysed the role of CTCs in blood at the first diagnosis of breast cancer and during adjuvant chemotherapy and endocrine treatment.
The researchers analysed blood samples from 1,767 node-positive and high-risk node-negative breast cancer patients before the start of their treatment, and compared the results to those obtained from 852 of the same patients after completion of chemotherapy.
We found that 10 percemt of patients whose blood was sampled before the start of treatment had more than one CTC, and 5 percent of these patients had more than two CTCs in approximately 20 ml of blood, Dr. Juckstock said.
The scientists found that among the 24 healthy individuals used as controls, none showed more than one CTC.
They said that among the 852 patients whose blood was analysed post-treatment, 11 percent were CTC positive before the start of treatment, while 7 percent had more than one CTC after completion of chemotherapy.
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More News on: Women and Cancer, Breast Biopsy, Pagets disease of the breast, Mastitis, Cancer and Homeopathy, Parkinsons Disease Surgical Treatment, Cysts and Tumours, Breast Cancer Facts, Cancer Facts, Cancer
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