Medindia

X

Chronic Pain - New Approaches

by Sheela Philomena on  March 11, 2011 at 3:24 PM Research News   - G J E 4
Researchers from University of California have discovered a cross-talk between two major biological pathways that are involved in chronic pain. This new research would pave way for novel methods to understanding and controlling chronic pain.
 Chronic Pain - New Approaches
Chronic Pain - New Approaches
Advertisement

The new study has revealed that analgesia mediated by inhibitors of the enzyme, soluble epoxide hydrolase (sEH), is dependent on a pain-mediating second messenger known as cyclic adenosinemonophosphate or cAMP.

Advertisement
"The interaction of many complex biological pathways is essential for the development of persistent pain, whether inflammatory or neuropathic," said lead researcher Bora Inceoglou of the Bruce Hammock lab, UC Davis Department of Entomology.

While conducting the research, the scientists found something they weren't looking for. "To our surprise, we found that cAMP interacts with natural EFAs and regulates the analgesic or pain activity of sEH inhibitors," Inceoglu said.This demonstrates the power of using advance instrumental analysis techniques to better understand the molecular mechanism of biological effects," said Nils Helge Schebb.

"This is like something old, something new, something practical and something basic, too," said Hammock, a distinguished professor of entomology who holds a joint appointment with the UC Davis Cancer Research Center.

The study has been published in the Proceedings of the National Academy of Sciences (PNAS).

Source: ANI
Advertisement

Post your Comments

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
User Avatar
* Your comment can be maximum of 2500 characters
Notify me when reply is posted I agree to the terms and conditions
Another treatment for chronic pain that many people don't know about is Low Level Lasers. FDA approved for chronic pain, the Erchonia laser is painless, penetrates the skin and stimulating the body's cells encouraging regeneration, which causes pain to decrease on an average of 60-70 percent.
sarahcrier Monday, March 14, 2011
And in many cases do not believe in you. They just think that you're a lazy or do for make feel bad people. This happens to me and that is why I turn to medications like vicodin or percocet, which will help to control pain. Although I mention a doctor of Findrxonline that these medicines are dangerous due to side effects and liver damage. I've done consulting my doctor and he told me that if I do it correctly I will not have problems later.
DamienWoody Friday, March 11, 2011

You May Also Like

Advertisement
View All

More News on: