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Cholesterol-lowering Drug Effective at Halting Early Atherosclerosis
Rosuvastatin arrested the progression of thickened carotid arteries compared to a placebo, said John R.Crouse, M.D., lead researcher and a professor of endocrinology at Wake Forest University School of Medicine. The findings show that the benefits of cholesterol management on arteries can be extended to low-risk patients.
Results from the study were reported today at the annual meeting of the American College of Cardiology in New Orleans and will appear in the March 28 issue of the Journal of the American Medical Association. The research involved people with moderately elevated cholesterol levels who didnt qualify for treatment under national guidelines.
Participants all had minimal thickening of their carotid arteries, which supply blood to the brain, and were considered at low risk for having a heart attack or dying from a heart-related event based on their age and other risk factors.
Over a two-year period, the therapy lowered low-density lipoprotein, or bad cholesterol, by 49 percent and increased high density lipoprotein, or good cholesterol, by 8 percent. Triglycerides were reduced by 16 percent and the progression of artery thickness was halted.
Rosuvastatin (sold under the trade name Crestor) is the newest member of a family of drugs known as statins that work to lower levels of cholesterol and other fats in the blood. Other statins have been tested with similar results in patients whove already had a heart attack or who had high cholesterol levels. This was the first study to evaluate Crestor in a group of people at low risk for heart attacks.
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More News on: Cholesterol, Drug Toxicity, Heart Attack, Signature Drug Toxicity, Cholesterol - The Enigma Chemical
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guest
03/28/2007
Thre are other substances that has the same effect as statins but without side effect risks. Cholesterol is not the problem though.
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