Researchers found that individuals exposed to higher levels of LDL ("bad") cholesterol or lower levels of HDL ("good") cholesterol during young adulthood were more likely to develop coronary calcium.
For example, 44 percent of study participants with an average LDL cholesterol level greater than 160 mg/dL had calcifications in their coronary arteries two decades later, compared to only eight percent of participants with optimal LDL levels less than 70 mg/dL.
In fact, even modest rises in LDL - as low as 100-129 mg/dL - were associated with a significantly higher risk of atherosclerosis, the study found. The majority of young adults studied (65 percent) had LDL levels higher than 100 mg/dL.
Participants were part of the Coronary Artery Risk Development in Young Adults study (known as CARDIA), which began in 1985 and involved healthy, young men and women of various backgrounds from four American cities. The study population was 47 percent African American and 56 percent female.
Atherosclerosis, or blockages in the coronary artery from cholesterol and plaque, can lead to heart attack and stroke.
The findings have been published August 2, 2010 in the Annals of Internal Medicine.
Source-ANI