Chemo, Thermotherapy Combo Shrinks Breast Cancer Tumours Faster

November 28, 2007 at 7:22 PM Cancer News
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Chemo, Thermotherapy Combo Shrinks Breast Cancer Tumours Faster
A new study has found that using microwave heat along with chemotherapy raises the effectiveness of the treatment when it comes to treating breast cancer.

The microwave treatment is based on technology originally developed at MIT in the late 1980s as a tool for missile detection.

In this study, large tumours treated with a combination of chemotherapy and a focused microwave heat treatment shrunk nearly 50 percent more than tumours treated with chemotherapy alone.

“It appears that heating the tumours drastically increased the effectiveness of the chemotherapy. The tumours shrank faster and died faster using the additional microwave hyperthermia on top of the chemotherapy,” said Dr. William C. Dooley, director of surgical oncology at the University of Oklahoma and the principal investigator of the study.

In the latest clinical trial, 15 patients received two microwave heat treatments, known as thermotherapy, along with four rounds of chemotherapy before surgery. The goal was to shrink tumours sufficiently to enable a breast-conserving lumpectomy procedure instead of the expected, and more invasive, mastectomy. Surgeons concluded that fourteen of the tumours shrunk enough for this to be possible.

In 1990, Dr. Alan J. Fenn, a senior staff member at MIT’s Lincoln Laboratory, adapted the thermotherapy treatment from a system that used focused microwaves to detect missiles and block out interfering enemy signals.

“It’s a very simple idea that can be applied to the treatment of many different cancers, including breast cancer,” Fenn said.

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