The researchers found that the total tumour weight, number of glands with tumours and fraction of mice with tumours were higher in those whose mothers who were fed corn oil.
The canola oil group displayed up-regulated genes for CCAAT-enhancer binding protein beta (CEBPß), a transcription factor involved in breast cancer differentiation, and Early growth response 1 (Egr1), a tumour suppressor gene.
The offspring of the canola oil-fed mothers showed higher levels of omega 3 fats in the inguinal fat pad, breasts and liver.
The study was presented at the American Association for Cancer Research's Seventh Annual International Conference on Frontiers in Cancer Prevention Research.
Source-ANI
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