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Cancerous Breast Lesions Better Identified With Combined Imaging Technologies
Researchers at Martinos Center for Biomedical Imaging at Massachusetts General Hospital in Boston helped develop a combined optical/x-ray imaging system capable of obtaining both structural and functional information of the breast.
The two technologies used were digital breast tomosynthesis (DBT), a three-dimensional application of digital mammography, and diffuse optical tomography (DOT), which measures levels of hemoglobin concentration, oxygen saturation and other cellular characteristics, based on how light from a near-infrared laser is absorbed and scattered within tissue.
"By co-registering optical and x-ray data, radiologists are able to map suspicious findings and analyze the functional characteristics of those areas," said lead researcher Qianqian Fang, Ph.D., a radiology instructor at Harvard Medical School.
In the study, combined DBT and DOT was performed on 189 breasts from 125 women with an average age of 56 years. To perform the procedure, an optical source and detector probes were attached to a DBT unit and, with the breast compressed, optical data was acquired. The optical probes were then removed without altering the breast compression and a DBT scan was performed.
"We are very excited about adding optical imaging to DBT, because it is low-cost, safe, noninvasive and fast," Dr. Fang said.
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More News on: Mastitis, Ganglion Cysts - Ganglion Wrist, Breasts - Structures and Types, Breast Lumps, Breast Lumps-Screening
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