Canadian scientist Ralph Steinman had expected to be awarded in earlier years, but when the news of his Nobel Prize for Medicine win was communicated on Monday, he had already passed away.
The 68-year-old cell biologist's own discoveries helped extend his life but he died Friday after a four-year battle with pancreatic cancer, his daughter told AFP.
"We said to him, 'Hang on until Monday,'" said Alexis Steinman, 34. "We joked, we said, 'You know you got to keep going until the Nobel.'"
She said the family was only alerted to Steinman's win when her mother discovered an email on his cell phone, which had been "turned to silent."
His hopes were raised a few years ago when he heard he was on the short list for the Nobel Prize. He did not win that year, she recalled, but the family has considered the possibility every year since.
Steinman shared the award with Bruce Beutler of the United States and Luxembourg-born Jules Hoffmann, a naturalized French citizen, for their work on the body's complex defense system in which signaling molecules unleash antibodies and killer cells to respond to invading microbes.
"The news is bittersweet, as we also learned this morning from Ralph?s family that he passed a few days ago after a long battle with cancer. Our thoughts are with Ralph's wife, children and family," said Marc Tessier-Lavigne, president of the New York-based Rockefeller University where he worked.