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CPAP Therapy Reduces Depression OSA Patients
October 16, 2007 at 6:02 PM
Research News
Daniel J. Schwartz, MD, of The Sleep Center at University’s Community Hospital in Tampa, Fla., surveyed patients referred to his sleep center for evaluation of OSA and who demonstrated a significant response to CPAP. The subjects were evaluated for symptoms of depression, were assessed again after four to six weeks of treatment with CPAP and then reassessed approximately one year later.
In this group of patients, the institution of CPAP therapy resulted in a significant decrease in those symptoms of depression that were assessed at both the short-term and long-term follow-up periods.
“Why the use of CPAP is associated with the changes in these symptoms is incompletely understood. Whether relief of the obstructive respiratory events with CPAP might ameliorate the symptoms by improving sleep continuity, by ameliorating the adverse effects of various neurotransmitters, by alleviating the adverse effects of any attendant hypoxemia, or by a mechanism as yet unknown, cannot be determined on the basis of the findings of our study. But, the data from our study suggests that successful CPAP therapy is associated with a statistically significant improvement in symptoms of depression, and that the improvement is sustained long term,” said Dr. Schwartz.
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