A study has found that two commonly used radiations treatments for early-stage, node-negative breast cancer - Partial-Breast Radiation Therapy (PBRT) and Whole-Breast Radiation Therapy (WBRT) – have no effect on a woman’s immune system.
The study led by Dr. Kevin Albuquerque, radiation oncologist at the Cardinal Bernardin Cancer Centre, Loyola University Health System, Maywood, Illinois, U.S.A, states that PBRT is a viable option for women for women.
“One of the first questions a woman newly diagnosed with breast cancer asks is ‘what impact will radiation have on my body?’ This study helps allay some fears,” Albuquerque said.
Traditionally, for early-stage, small-tumour, node-negative breast cancer whole-breast radiation therapy has been the standard of care.
“PBRT is a viable option for women who are eligible,” Albuquerque said.
In the study, 30 women, over 45 years of age, who had a lumpectomy for early stage, small-tumour, node-negative breast cancer were divided into two treatment groups: the Whole-Breast Radiation Therapy group and the partial-breast radiation therapy group.
During the study, the researchers conducted psychological tests to all the participants five times: first, before any initiation of radiation therapy; second, at three weeks after completion of radiation therapy; and then at six-, nine- and 15-weeks post therapy.
The group of tests included one measuring tension, depression, anger, vigour and fatigue.
Another measured well being at the emotional, physical, functional and social levels.