About Us Portfolio Press Careers Sitemap Advertise Contact Us Make this your Homepage

Custom Search

Register

Sign In

Sign In Using Facebook

Home » Mental Health News

Breast Cancer Medication Reduces Manic Phase of Bipolar Disorder

September 17, 2007 at 6:02 PM Mental Health News

The medication tamoxifen, best known as a treatment for breast cancer, dramatically reduces symptoms of the manic phase of bipolar disorder more quickly than many standard medications for the mental illness, a new study shows. Researchers at the National Institutes of Health�s National Institute of Mental Health (NIMH) who conducted the study also explained how: Tamoxifen blocks an enzyme called protein kinase C (PKC) that regulates activities in brain cells. The enzyme is thought to be over-active during the manic phase of bipolar disorder.

Related Links

By pointing to PKC as a target for new medications, the study raises the possibility of developing faster-acting treatments for the manic phase of the illness. Current medications for the manic phase generally take more than a week to begin working, and not everyone responds to them.

Tamoxifen itself might not become a treatment of choice, though, because it also blocks estrogen � the property that makes it useful as a treatment for breast cancer � and because it may cause endometrial cancer if taken over long periods of time. Currently, tamoxifen is approved by the Food and Drug Administration for treatment of some kinds of cancer and infertility, for example. It was used experimentally in this study because it both blocks PKC and is able to enter the brain.

Results of the study were published online in the September issue of Bipolar Disorders by Husseini K. Manji, MD, Carlos A. Zarate Jr., MD, and colleagues.

Page 1

Page 1 | 2

Next

Future Jets may Become More Environment Friendly With the Use of Coal, Biomass

News Drug That Destroy Cancer Cells With Few Side-effects Developed

More News on: Women and Cancer, Drug Toxicity, Breast Biopsy, Pagets disease of the breast, Mastitis, Breast Cancer Facts, Breasts - Structures and Types, Breast Lumps, Breast Lumps-Screening, Breast Cancer

Comment & Contribute

Be the first to comment!
Comments should be on the topic and should not be abusive. Comments are normally moderated and are reviewed after they are posted.
* Your comment can be maximum of 2500 characters
	Notify me when reply is posted I agree to the terms and conditions
Your comments are automatically posted once they are submitted. All comments are however constantly reviewed for spam and irrelevant material (such as product or personal advertisements, email addresses, telephone numbers and website address). Such insertions do not conform to our policy and 'Terms of Use' and are either deleted or edited and republished. Please keep your comments brief and relevant.This section may also have questions seeking help. If you have the information you are welcome to respond, but please ensure that the information so provided is genuine and not misleading.

Medwonders Health Network

Support Groups Members Discussions

Total Members - 54371
Support Groups - 445

Health News Index

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Latest News Most Popular Most Commented

Soy Supplements may Not Protect Against Breast Cancer

New Treatment Offers Hope for Leishmaniasis

Blood Fat Levels Could Predict Stroke In Postmenopausal Women

Regular Intake of Vitamins and Minerals Prevent Colon Cancer

CDC Report Says Cost of Child Abuse Comparable to Diabetes

News Archive
Date :
Category :
Keyword :

Quiz on Cancer
Looking for information on cancer? Go through medindia's Cancer quiz.

News Quick Links

	News Central			Health Watch
	Latest Health News			Health In Focus
	News Category (500+)			Breaking Health News
	Popular News			Celebrating Life
	Health News and Press Release			Medindia - Exclusive
	News Photo Gallery			India Special
	News Video Gallery			Lifestyle and Wellness
	News From Other Resources

Breast Cancer

Complete Medindia Resources

News Categories:


»	Consumer Watchdog Wants California to Regulate Health Insurance Hikes

»	DSGMC Announces Health Insurance Scheme

»	IRDA Urges Insurers to Launch More 'Day-Care' Based Covers

»	Germans Looking to Switch From Private to National Health Insurance

»	Will US College Students Have Access to Free Birth Control?
More Insurance News

Mental Health Related News
»	Surprise Location of Brain's Speech Centre Than Believed	»	Retarding Age-Related Neural Timing can be Equalised by Music Training
»	Blood Test May Soon Help Diagnose Major Depression Accurately	»	Short-term Memory Enabled by Complex Interplay of Different Brain Regions: Study
»	New Insight on Alzheimer's Disease Spread in Different Brain Regions	»	Skin Samples Used in Creating Human Brain Cells
»	How Testosterone Spoils Our Attempts to Work Together	»	Schizophrenia Research: A Route to the Brain Via Nose

Read More >>

Accident and Trauma Care Support Group	Acupuncture Support Group	Albinism / Hypopigmentation / Albinos Support Group
Alcohol abuse / Alcohol dependence / Alcoholism Support Group	Aromatherapy Support Group	Avian Influenza / Bird Flu Support Group
Ayurveda Support Group	Benign Prostatic Hyperplasia Support Group	Birth Defects - Metabolic Defects Support Group

Breast Cancer Medication Reduces Manic Phase of Bipolar Disorder

Medwonders Health Network

Mental Health Related News

Consumers

Medical Professionals

Medical Students

Directories