A pair of Los Alamos National Laboratory researchers have developed a new mathematical tool that may help health experts and crisis managers know if Bird Flu, or avian influenza H5N1, may spread globally or not.
Luís Bettencourt and Ruy Ribeiro of Los Alamos Theoretical Division have come up with a novel approach to see subtle changes in epidemiological data to gain insight into whether bird flu can turn into a deadly global pandemic.
What we wanted to create was a mathematically rigorous way to account for changes in transmissibility. We now have a tool that will tell us in the very short term what is happening based on anomaly detection. What this method wont tell you is whats going to happen five years from now, said Bettencourt.
The duo started their study three years ago when the world was wondering whether avian influenza H5N1, with its relatively high human mortality rate, could become a frightening new pandemic, an many experts fearing if the virus could evolve into a form that would become transmissible from human to human.
The researchers wanted to create a smart methodology to look at changes in disease transmissibility, and for this, they developed an extension of standard epidemiological models that describes the probability of disease spread among a given population.
Then the model considered actual disease surveillance data gathered by health experts like the World Health Organization and looked for anomalies in the expected transmission rate versus the actual one. And thus, the model provides health experts actual transmission probabilities for the disease, based on this information.