Blood Test to Help Determine the Efficacy of Anti-depressant

by Dr. Trupti Shirole on  December 18, 2011 at 4:00 PM Mental Health News
RSS Email Print This Page Comment
Font : A-A+

A blood test for a protein called Vascular Endothelial Growth Factor (VEGF) can predict whether an anti-depressant drug will work on a depressed patient or not, according to researchers at the Loyola University Medical Center in Illinois, US.
 Blood Test to Help Determine the Efficacy of Anti-depressant
Blood Test to Help Determine the Efficacy of Anti-depressant

The study involved 35 patients who took the anti-depressant Escitalopram (selective serotonin reuptake inhibitors, SSRIs) for major depressive disorder. It was seen that more than 85% of depressed patients who had higher than normal blood levels of VEGF, experienced partial or complete relief after taking escitalopram, as compared to fewer than 10% of depressed patients who had low levels of VEGF responded to the drug.

Currently 60% of depression patients do not respond well to the first drug prescribed and it can take a month to achieve a drug response. Such blood tests promise a considerable improvement in time to benefit.

Lead author of the study, Angelos Halarissaid, "This would be the first time we would have a predictor for how well a patient would respond to an anti-depressant. It would greatly benefit our patients if we could predict ahead of time whether a given medication would be effective for a certain patient."

Presently VEGF blood test is very expensive, but the cost is likely to come down significantly if this test becomes widely used.

Source: Medindia

Post a Comment

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
* Your comment can be maximum of 2500 characters
Notify me when reply is posted
I agree to the terms and conditions

More News on:

Thalassemia Varicocele Quiz on Depression Hypermobility Syndrome Blood in Stools - Symptom Evaluation Bombay Blood Group 

News A - Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

News Search

Medindia Newsletters

Subscribe to our Free Newsletters!

Terms & Conditions and Privacy Policy.

Stay Connected

  • Available on the Android Market
  • Available on the App Store

Facebook

News Category

News Archive