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Blood Sugar Control Does Not Lower Heart Attack, Stroke Risk in Some Diabetics
Researchers did find, however, that firm glucose control defined as keeping hemoglobin levels, or A1C, below 7 percent may reduce cardiovascular issues for diabetics with fewer and less severe health problems.
Study co-leader Dr. Sheldon Greenfield, Donald Bren Professor of Medicine at UCI and co-executive director of the Health Policy Research Institute, said the findings coupled with prior research suggest that guideline developers and physicians should account for a patient's other conditions in determining diabetic treatment goals. An earlier federal study found that lowering blood sugar too quickly or too much could harm or even kill some diabetics.
"We believe that in certain cases doctors should aim for just moderate blood glucose levels and aggressively treat coexisting conditions," said Greenfield.
Study co-leader Sherrie Kaplan, associate dean at UCI's School of Medicine, said the results help explain inconsistencies in previous studies on whether an under-7 A1C decreases heart attack and stroke risk in diabetics. Some have shown that it does, and some have indicated no such link.
"The findings reveal that strict glucose control benefits some patients but not others depending on certain factors, mainly concurrent illnesses," said Kaplan, co-executive director of the Health Policy Research Institute. "They also raise serious questions about guidelines advocating a single approach for all diabetics."
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