Blind Mole Rat May Serve As 'Living Tumour' In Cancer Research

by Sreeraman on  March 06, 2009 at 2:48 PM Research News
  •   Print
  •   Share
  •   Comments
  •  Text 
Blind Mole Rat May Serve As 'Living Tumour' In Cancer Research
If someone ever calls you a "dirty rat," consider it a compliment. A new discovery published online in the FASEB Journal shows that cellular mechanisms used by the blind mole rat to survive the very low oxygen environment of its subterranean niche are the same as those that tumors use to thrive deep in our tissues. The net effect of this discovery is two-fold: first the blind mole rat can serve a "living tumor" in cancer research; and—perhaps more important—that unique gene in the blind mole rat becomes a prime target for new anti-cancer drugs that can "suffocate" tumors.

"President Obama said in his February 24 address to the U.S. Congress that he wants to put an end to cancer, and the boost to basic science in the stimulus package is a great start," said Gerald Weissmann, M.D., Editor-in-Chief of the FASEB Journal. "But if he wants to end the longest ongoing war in U.S. history—a War on Cancer we've been fighting since before Nixon declared it in 1971—then building on this discovery is a good place to start."

To reach their finding, American and Israeli scientists from the Universities of Illinois and Haifa conducted experiments in multiple groups of "dirty" mole rats and "regular" rats. For each type of animal, a control group was exposed to normal levels of oxygen while the experimental groups were exposed to oxygen levels ranging from 3 percent to 10 percent.

Page 1 Page 1 | 2  Next
 Email Email   RSS Feeds RSS Feeds   Print this page Print   Save this page Save   Link Link   Syndicate Syndicate   Comments Comments   Bookmark and Share
 
Comment & Contribute
Comments should be on the topic and should not be abusive. Comments are normally moderated and are reviewed after they are posted.
* Your comment can be maximum of 2500 characters

Notify me when reply is posted
I agree to the terms and conditions
  
If you have a question about health related issues, you can now post it in our Ask An Expert section on our community website Medwonders.com and get answers from our panel of experts.
X
  • Health News Index
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
News Archive
Date :
Category :
Keyword :
Quiz on Cancer
Looking for information on cancer? Go through medindia's Cancer quiz.
  • News Quick Links
News Central Health Watch
Latest Health News Health In Focus
News Category (500+) Breaking Health News
Popular News Celebrating Life
Health News and Press Release Medindia - Exclusive
News Photo Gallery India Special
News Video Gallery Lifestyle and Wellness
News From Other Resources
Cancer
Complete Medindia Resources
News Categories:  
Obesity Health Center

Research Related News

» Lack of Vitamin D in Diet Raises Stroke Risk in Japanese-Americans » Why Bovine TB Continues to Spread Demystified in New Research
» Seaweed Pill May Help Treat Arthritis » P. Aeruginosa Infection Leads to Worse Outcomes and Increased Hospitalizations in COPD Patients
» Hormone Boosts Production of Molecules Which Fight Skin Infection » Protein Discovery Could Lead To New Vaccine for Meningitis
» Qui Vive: Intense Nuclear Radiation Threat, Scientists » 'Miracle' Diet of Reverse Engineering Epilepsy
Read More >>