Researchers know that the integrity of the brain's white matter is compromised in adult alcoholics, but it is unclear when during the course of drinking white matter abnormalities begin to manifest themselves. However, white matter has been shown to continue developing throughout young adulthood.
Tapert and colleagues used an MRI technique called diffusion tensor imaging, or DTI, to measure the integrity of white matter in the brains of 28 teenagers - 14 who had and 14 who did not have histories of binge drinking. DTI, which is sensitive to the random movement of water in cells or a target tissue, allowed the researchers to observe alterations to the structure of fibers within the brain's white matter.
The 28 participants were age16 to 19, and none had a history of an alcohol or other drug use disorder. Binge drinkers were 14 of the teens who reported drinking at least four (for females) or five (for males) alcoholics beverages in one sitting during the three months prior to DTI imaging. The control teens were matched on age, gender and level of education.
According to Tapert, the teen binge drinkers exhibited lower levels of white matter fiber coherence, as measured in 18 separate areas of the brain, relative to the controls.
"Those who reported engaging in binge drinking showed lower levels of brain organization," said Tapert. She added that this could be either a risk factor for increased alcohol use or an effect of the alcohol. "While long-terms studies that follow teens over time are essential to clarify the cause and effect of these brain changes, I would say that drinking to the point of being drunk may be detrimental to the adolescent brain."
Source-Newswise
SRM