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Beta Blockers May Increase Risk for Surgical Anemia Complications
Blood loss and anemia are very common in patients during and after surgery; more than 30 percent of patients undergoing moderate- to high-risk surgery experience a significant drop in blood levels. The normal response of a patient''s body during significant blood loss is to increase cardiac output through increased heart rate to ensure sufficient delivery of oxygen to organs.
Beta blockers are used to treat a variety of conditions, including high blood pressure, heart attack, glaucoma and migraines. The medication works to reduce the heart rate, reducing blood pressure as a result. Beta blockers are often prescribed for patients around the time of surgery to provide protection of the cardiovascular system.
"Beta blockers are known to reduce death from cardiac complications after noncardiac surgery and have been recommended for patients with clinical risk factors. However, previous studies such as the POISE (Perioperative Ishemic Evaluation) trial published in the May 31, 2008 Lancet have revealed that increased stroke rates and mortality were associated with blood loss in patients treated with high doses of beta blockers," said W. Scott Beattie, M.D., Ph.D., F.R.C.P.C., Fraser Elliot Chair in Cardiac Anesthesia, University Health Network, Toronto General Hospital in Toronto, Ontario, Canada.
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