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Best Blood Glucose Levels for Diabetics With Kidney Failure
For most patients with diabetes, taking medication to lowering blood levels of hemoglobin A1C, which reflect average blood glucose levels, to <7% can lower their risk of developing certain complications. Sylvia Paz Ramirez, MD (Arbor Research Collaborative For Health) and her colleagues wondered whether this holds true for diabetic patients who have developed kidney failure.
The researchers analyzed data from 8,437 dialysis patients from 12 countries who had diabetes. They found that the lowest risk of death during the study occurred when hemoglobin A1C levels were between 7% and 8%. Both high and low levels were linked with increased rates of death, particularly for patients with levels of 9% or higher or less than 5%. Among patients with A1C levels below 7%, death rates were higher among patients taking diabetes medications.
In a similar study, Miklos Molnar MD, PhD (Semmelweis University, in Budapest, Hungary) and his team examined death rates among 54,757 diabetic patients treated at DaVita dialysis clinics from July 2001 through June 2006 with follow-up through June 2007. They found a link between high death rates and hemoglobin A1C levels of 8% or greater. Very low levels also increased patients'' risk of dying during the study.
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