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Home » Research News

Bacteria can be Deadly to Wound-treating Maggots

by Rajshri on February 07, 2010 at 9:54 AM Research News

Bacteria that infect chronic wounds can be deadly to maggot 'biosurgeons' used to treat the lesions, says a new study..

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Experts at Copenhagen Wound Healing Centre, Statens Serum Institut and the University of Copenhagen in Denmark, observed in their study that the maggots applied to simulated wounds heavily infected with the bacterium Pseudomonas aeruginosa were left dead after 20 hours.

P. aeruginosa is associated with chronic wounds in which the bacteria clump together to form biofilms.

By effectively talking to each other via a well-studied communication system called quorum sensing (QS), bacteria in biofilms are known to be more successful at avoiding destruction by the host immune system as well as antibiotics.

Dr Anders Schou Andersen, who led the research, explained: "When we blocked the QS signalling pathways in the bacteria, the maggots were much better at surviving and potentially cleansing the wounds.

"Signalling between bacteria growing in biofilms is known to lead to the production of lethal toxins, without which the bacteria are more vulnerable to eradication."

Maggots have been used to disinfect wounds since ancient times, but it gained popularity in the early 1990s.

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Bacteria can be Deadly to Wound-treating Maggots

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