Autoimmune Response in Multiple Sclerosis

July 13, 2007 at 4:50 PM Genetics & Stem Cells News
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The second clonotype, BV16/BJ2S5, persisted following recovery, consistent with the hypothesis that the other, BV8S2/BJ2S7 T cell clonotype, is the driver of disease and necessary for EAE/MS persistence. The identification of this T cell subset suggests that these cells may be critical targets valuable to the design of therapies for autoimmune diseases such as MS.

AUTHOR CONTACT: Eli E. Sercarz Torrey Pines Institute for Molecular Studies, San Diego, California, USA. Phone: (858) 455-3824; Fax: (858) 455-3715; E-mail: esercarz@tpims.org

Source-Eurekalert
JAY/M
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