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Australian Researcher Develops Non-invasive Technique to Detect Liver Flukes

by Gopalan on February 14, 2009 at 1:07 PM General Health News

A researcher with the University of Queensland has developed a non-invasive screening method for potentially fatal liver and intestinal flukes.

Flukes are parasitic flatworms that can infest humans and an estimated 9 million people are supposed to be affected in southeast Asia.

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The leaf-shaped flukes enter the human digestive tract though consumption of raw fish, an important cultural practice which continues despite authorities warning against it.

The creatures' life cycles involve marine snails and even dogs and cats depending on the species of fluke.

In extreme cases, the flukes can cause cancer of the bile duct and/or painful stones in the bile duct, leading to liver disease and even death.

The highly accurate test can identify the species involved from one gene from an egg of a fluke among billions of other genes in a single faecal sample.

The breakthrough test is a vast improvement on existing testing methods to identify the flukes, involving a painful process of inducing people to purge fully grown flukes.

The test also allows authorities to more effectively handle infestations once they know the particular species, its life cycle and host animals if any.

The PCR test is already being used by Thai researchers to screen people for the presence of three species of liver and intestinal flukes which range in length from a few millimetres to one centimetre.

Dr Rebecca Traub and Dr Julie Macaranas, from UQ's School of Veterinary Science, developed the test after field work in Thailand, testing samples from more than 300 people in a remote village, 150km east of Bangkok.

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Australian Researcher Develops Non-invasive Technique to Detect Liver Flukes

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