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Australian Firm’s Natural Antibody Drug Promising
Antibodies (also known as immunoglobulins) are gamma globulin proteins that are found in blood or other bodily fluids of vertebrates, and are used by the immune system to identify and neutralize foreign objects, such as bacteria and viruses.
The recently completed studies were conducted by independent researchers and were designed to test PAT-SM6’s ability to prevent the metastatic spread of colon cancer to the liver.
The natural human antibody PAT-SM6 has been shown to have potent anti-cancer properties in a large number of laboratory and animal studies. PAT-SM6 binds to a proprietary cancer associated disease target that is expressed on the surface of cancer cells but not healthy tissues.
In the 19 animals treated with PAT-SM6, the median number of tumours that spread from the colon to the liver was decreased by approximately 50% as compared to the corresponding control group. This statistically significant result demonstrates the promise of PAT-SM6 as an effective treatment for the prevention of colon cancer metastases.
Dr. Christoph Otto, a medical oncologist and one of the lead investigators for the preclinical studies, said “the results of these studies indicate that PAT-SM6 offers great potential in terms of preventing colon cancer metastases, which is critically important because in most cases it is the spread of colon cancer to other organs that ultimately kills the patient.”
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