Arterial Clotting may be Prevented by Carbon Monoxide

by Rajashri on  June 25, 2009 at 7:39 PM Research News
RSS Email Print This Page Comment
Font : A-A+

 Arterial Clotting may be Prevented by Carbon Monoxide
A new study has shown that carbon monoxide can protect against arterial clotting despite its ill-effects on the rest of the body.

Carbon monoxide is extremely poisonous, and can inhibit the exposure of oxygen, resulting in death.

However, the researchers have shown that inflamed or injured tissues up regulate heme oxygenase-1 (HO-1), a protein that both protects cells and produces CO, suggesting that low levels of CO may have protective effects.

During the study, Chen et al examined clotting mechanisms in mice that received arterial transplants.

They found that absence of HO-1 in these mice resulted in significant mortality due to arterial clotting; however, treatment with a CO-releasing molecule both decreased clotting and improved survival.

The researchers concluded that HO-1/CO plays an "important role ...[in] protection against vascular arterial thrombosis in murine aortic allotransplantation."

The study appears in the American Journal of Pathology.

Source: ANI
RAS

Post a Comment

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
Notify me when reply is posted
I agree to the terms and conditions

More News on:

Charcoal 

News A - Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

News Search

Medindia Newsletters

Subscribe to our Free Newsletters!

Terms & Conditions and Privacy Policy.

Advertisement
Advertisement

Stay Connected

  • Available on the Android Market
  • Available on the App Store

Facebook

News Category

News Archive