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An Element Of Cough Supressant, Proved Effective In Treating Advanced Prostate Cancer

by priya on December 22, 2008 at 1:22 PM Drug News

An ingredient present in a common cough suppressant has been found to be effective in the treatment of advanced prostate cancer, according to a new study.

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The collaborative study revealed that noscapine, which has been used in cough medication for nearly 50 years, reduced tumour growth in mice by 60 percent and limited the spread of tumours by 65 percent without causing harmful side effects.

While prostate cancer is slow growing in most men, it is considered advanced when it spreads beyond the prostate. There is no known cure.

The laboratory study was a joint effort by Dr. Israel Barken of the Prostate Cancer Research and Educational Foundation, Moshe Rogosnitzky of MedInsight Research Institute, and Dr. Jack Geller of The University of California San Diego.

Noscapine has previously been studied as a treatment for breast, ovarian, colon, lung and brain cancer and for various lymphomas, chronic lymphocytic leukemia and melanoma. However, this is the first study to demonstrate its effectiveness in treating prostate cancer.

Noscapine is a naturally-occurring substance, a non-addictive derivative of opium. As a natural substance, noscapine cannot be patented, which has limited the potential for clinical trials.

Since noscapine is approved for use in many countries as a cough suppressant, however, it is available to doctors to prescribe for other uses as well. This common practice is known as "off-label" prescription. Noscapine is increasingly being used off-label to treat a variety of cancers.

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An Element Of Cough Supressant, Proved Effective In Treating Advanced Prostate Cancer

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