Scientists say that vitamin D may be an effective therapy to treat and even prevent allergy to a common mold that can cause severe complications for patients with cystic fibrosis and asthma.
The findings are based on a study, conducted by researchers from Children's Hospital of Pittsburgh of UPMC, the University of Pittsburgh School of Medicine and Louisiana State University School of Medicine.
Aspergillus fumigatus, is one of the most common airborne molds and while it does not cause illness in the vast majority of those who inhale it, it can cause life threatening allergic symptoms in patients with cystic fibrosis.
As many as 15 percent of patients with cystic fibrosis will develop a severe allergic response, known as Allergic Bronchopulmonary Aspergillosis (ABPA). Some patients with asthma also can develop ABPA.
The research team, led led by Jay Kolls, a lung disease researcher at Children's Hospital and professor of pediatrics at the University of Pittsburgh School of Medicine, studied cystic fibrosis patients from the Antonio J. and Janet Palumbo Cystic Fibrosis Center at Children's Hospital who had A. fumigatus infections. One group had developed ABPA, while the other hadn't.