Adherence Counseling During HIV Treatment Improves Patient Outcomes

by Sheela Philomena on  March 4, 2011 at 1:05 PM AIDS/HIV News   - G J E 4
During HIV treatment, intensive adherence counseling significantly reduces poor adherence and virologic treatment failure , says a study. As poor adherence to HIV treatment can lead to drug resistance and inadequate treatment, it is necessary to identify interventions to improve adherence that are inexpensive and proven to be effective in resource-limited settings.
 Adherence Counseling During HIV Treatment Improves Patient Outcomes
Adherence Counseling During HIV Treatment Improves Patient Outcomes

The findings of this study define an adherence counseling protocol that is effective; these findings are relevant to other HIV clinics caring for large numbers of patients in sub-Saharan Africa.

The authors randomised 400 patients who were newly diagnosed with HIV and had never before taken antiretroviral therapy to receive adherence counseling alone; alarm device alone; both adherence counseling and alarm device together; and a control group that received neither adherence counseling nor alarm device.

Patients had baseline blood taken to test for HIV-1 RNA and CD4 count and blood was then taken every 6 months for the duration of the study (18 months). After starting HIV treatment, patients returned to the study clinic every month with their pill bottles for the study pharmacist to count and record the number of pills remaining in the bottle. The study is published in PLoS Medicine by Michael Chung from the University of Washington, Seattle, USA, and colleagues.

Patients receiving adherence counseling were 29% less likely to experience poor adherence compared with those who received no counseling. Furthermore, those receiving intensive early adherence counseling were 59% less likely to experience virologic treatment failure. However, there was no significant difference in mortality or significant differences in CD4 counts at 18 months follow-up between those who received counseling and those who did not. There were also no significant differences in adherence, time to virologic treatment failure, mortality, or CD4 counts in patients who received alarm devices compared with those who did not.

The authors conclude: "As antiretroviral treatment clinics expand to meet an increasing demand for HIV care in sub-Saharan Africa, adherence counseling should be implemented to decrease the development of treatment failure and spread of resistant HIV."

Source: Eurekalert

Post your Comments

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
User Avatar
* Your comment can be maximum of 2500 characters
Notify me when reply is posted I agree to the terms and conditions
HIV/AIDS is not actually a death sentence. It is a disease that can be managed and be controlled by the individual who acquired it allowing him to live a long normal and productive life like anyone else. POZmingle the largest dating and support site for HIV singles claim that they have 200,000 HIV members, Most of them are here to find understanding, support and love. It is really a good thing that encourage each other, Leading a healthy life.
juliarix Saturday, March 5, 2011

You May Also Like

View All