40 Percent of Community Pharmacists Dispensed Off-label Drug

July 13, 2007 at 12:40 PM Drug News
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40 Percent of Community Pharmacists Dispensed Off-label Drug
Forty per cent of community pharmacists have dispensed an off-label drug to a child in the last month, according to research published in the July issue of the British Journal of Clinical Pharmacology.

And although 78 per cent said they would tell a family doctor that the prescription they had written would have to be dispensed off-label – outside the terms of the drug’s product license – only 66 per cent felt they had a similar responsibility to inform the child’s parents.

Pharmacists said the most common off-label dispensing of prescribed and over-the-counter medicines involved giving a drug to a child who was younger than the recommended minimum age for the drug or giving them higher than the recommended dose.

Just under 500 community pharmacists, with wide-ranging experience and post-registration education, took part in the research, carried out by the Department of Medicine and Therapeutics at the University of Aberdeen, UK.

“The community pharmacists who responded to the questionnaire appeared to be aware of – and concerned by - the issues surrounding off-label prescribing to children” says co-author Dr James McLay.

“What did concern us was that only 40 per cent of pharmacists said they had dispensed off-label medicines to children in the month before the survey.“Having reviewed primary care prescribing levels, this 40 per cent figure was lower than expected and leads us to conclude that many pharmacists may not realise that they are dispensing off-label.

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