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3-D Visualization of Cells Through Microscope may Revolutionize Cancer Detection
The researchers say that the technique may bridge a widening gap between cutting edge imaging techniques used in research and clinical practices.
Associate Professor Eric Seibel and his colleagues carried out this work in collaboration with a private company called VisionGate, which holds the patents on the technology.
The have revealed that the machine works by rotating the cell under the microscope lens, taking hundreds of pictures per rotation, and then digitally combining them to form a single 3-D image.
According to them, the 3 D visualizations may lead to big advances in early cancer detection, since clinicians today identify cancerous cells by using 2-D pictures to assess the cells' shape and size.
It's a lot easier to spot a misshapen cell if you can see it from all sides. A 2 D representation of a 3 D object is never perfectly accurate imagine trying to get an exact picture of the moon, seeing only one side, Seibel said.
The new microscope is known by the trademarked name Cell CT because it works similarly to a CT scan, though on a very small scale.
In a CT scan, the patient is immobile while the X-ray machine rotates.
In the Cell CT microscope, each cell is embedded in a special gel inside a glass tube that rotates in front of a fixed camera that takes many pictures per rotation.
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