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What is Bud-chiari Syndrome ?  

A condition that occurs due to occlusion of hepatic veins that drain the liver. Thrombosis of hepatic veins could occlude them. The syndrome can be fulminant (sudden onset, quick progression to intense to the point of being fatal), acute, chronic or asymptomatic.

Cause(s) :  
  • Thrombosis of hepatic vein
  • Pregnancy and Postpartum state
  • Connective tissue disorders
  • Use of oral contraceptives
  • Paroxysmal nocturnal hemoglobinuria (destruction of red blood cells by a part of body’s intrinsic immune system)
  • Polycythemia vera (a type of blood cancer where bone marrow makes too many red blood cells)
  • Liver cancer
  • Lupus anticoagulants
  • Injury
Symptoms :  
  • Classic triad - Abdominal pain, Ascites and Hepatomegaly
  • Jaundice
  • Ankle edema
  • Renal failure
  • Hepatic necrosis
  • Lactic acidosis
Diagnosis and Tests :  
  • Liver enzymes measures
  • Blood test
  • CT
  • MRI
  • Ultrasonography
  • Retrograde angiography
  • Venography
Category :  Reticulo-endothelial & Hematological

Specialist to consult :  Hepatology

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