A rare sleep disorder with persistent episodic hyperosmia [excessive daytime sleepiness] and cognitive or mood changes. The episodes of sleepiness occur for more than a week at a time, and the condition may last for more than a decade.
Cause(s) : Possible causes are:
Circadian rhythm (sleep cycle) dysfunction
Disturbances in thalamus, temporal lobe and frontal lobe.
Dysfunction in the metabolism of serotonin and dopamine.
Multifocal, localized encephalopathy
Excessive tiredness and prolonged sleep (hyperosmia)
Excessive appetite (hyperphagia)
Overt sexual behaviours like exposing oneself, using obscene language, fondling genitalia and making unwanted sexual advances
Compulsive behaviours like body rocking, chewing lips, compulsive writing on walls, stripping down wallpaper, etc.
Severe apathy and derealization [alteration in the perception of the external world so that it seems unreal]
Depression and anxiety
Some patients act childish during episodes
Communication and coordination skills are disturbed during episodes
Diagnosis and Tests : KLS is a diagnosis of exclusion, by eliminating certain symptoms and diseases.
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