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Other Names :  

Goodpasture’s disease, anti-glomerular basement antibody disease, or anti-GBM disease

What is Goodpasture's Syndrome ?  

A rare autoimmune disease in which antibodies attack our own lungs and kidneys. Bleeding from the lungs.

Cause(s) :  
  • An insult to the blood vessels taking blood from and to the lungs could establish anti-glomerular basement membrane to come into contact with the alveoli. The insult could be due to exposure to various chemicals like metal dust inhalation, smoke, hydrocarbons, cocaine, etc.
  • High-oxygen environments are also known to cause this syndrome.
  • Infections such as influenza A.
Symptoms :  
  • Weight loss
  • Fatigue
  • Fever and chills
  • Joint pain

Lung symptoms: usually precede kidney symptoms
  • Chest pain
  • Coughing up blood
  • Shortness of breath

Kidney symptoms:
  • Blood in the urine
  • Protein in the urine
  • Swelling of limbs or face
  • High levels of urea in blood
  • High blood pressure
Diagnosis and Tests :  
  • Lung Biopsy
  • Kidney Biopsy
  • Chest X ray
  • Blood test
  • Urine analysis
Category :  Congenital Conditions

Specialist to consult :  Pulmonology

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