Tuberculosis (TB) vaccines reducing TB patients

Wednesday, December 16, 2009 Medical PDA News J E 4
Tuberculosis has been known with different names, since ancient times. The ancient disease called phthisis has references of symptoms, similar to that of TB. Later, it was also known as 'consumption' because a person used to just 'waste away' after contracting the disease.

A disease called white plague that occurred in Europe, in the 17th century, was actually tuberculosis. It was called so because loss of skin color was observed in patients. The name 'tuberculosis' was used, for the first time, in the 19th century. It is believed to have originated from the word 'tubercle', meaning a 'protuberance, swelling or nodule'. In this case, such nodules are found in lungs or on bones.

The researchers developed the new TB vaccine using a genetically modified adenovirus – a virus responsible for the common cold. After removing a small portion of the gene, they inserted part of the TB gene responsible for immunity.


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