Scientists at Invictus Oncology Design Targeted Therapy for Cancer Treatment

Monday, March 13, 2017 Cancer News
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DELHI, India, March 13, 2017 /PRNewswire/ --

Scientists at Invictus Oncology Pvt. Ltd. have utilized a novel linker

chemistry to generate antibody-drug conjugates which act like 'magic bullets', a concept proposed by Nobel laureate, Paul Ehrlich. This technology can provide a targeted therapy to cancer patients whereby the antibody can
home into specific markers or 'addresses' expressed by cancer cells to deliver extremely toxic drugs. The major challenge in the field has been to define an optimal linker chemistry that prevents the drug from breaking off from the antibody in the bloodstream but releases the drug once it reaches the tumor. The linker chemistry developed by Invictus team enables the combination of biologically active anti-cancer drugs and tumor-targeting antibodies, providing a sensitive distinction between normal and tumor cells. Utilizing this novel technology, the therapy minimizes side effects and maximizes antitumor efficacy. The lead author of the paper, which was published in the March 2017 issue of Chemical Science (Chem. Sci., 2017,8, 2387-2395), is Nimish Gupta, Scientist II at Invictus Oncology. The paper's senior authors are Monideepa Roy, Director-R&D, Invictus Oncology and Shiladitya Sengupta, Faculty Member at Harvard Medical School and Co-founder of Invictus.

About Invictus Oncology Private Limited 

Invictus Oncology is a biopharmaceutical company based in Delhi, India focused on the development of novel therapeutics for cancer treatment. Invictus was co-founded by Harvard Medical School's Dr. Shiladitya Sengupta and Padma Vibhushan Dr. Raghunath A. Mashelkar.

Invictus has assembled a world-class management and scientific team, alongside a Board of Directors and Scientific Advisory Board that collectively have a significant track record of conducting acclaimed scientific research, developing breakthrough products and building sustainable businesses. Invictus is backed by Navam Capital, Aarin Capital and Ratan Tata.

Media Contact: Monideepa Roy [email protected] Invictus Oncology Private Limited

SOURCE Invictus Oncology Private Limited



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