Rigel to Present at the Piper Jaffray Annual Health Care Conference

SOUTH SAN FRANCISCO, Calif., Nov. 25 RigelPharmaceuticals, Inc. (Nasdaq: RIGL) today announced that Raul Rodriguez,Rigel's executive vice president and chief operating officer, will present acompany overview at the Twentieth Annual Piper Jaffray Health Care Conferenceon Wednesday, December 3, 2008 at 3:00 p.m. EST at The New York Palace Hotelin New York City.

To access the live audio webcast or the subsequent archived recording, logon to http://www.rigel.com. Please connect to Rigel's website several minutesprior to the start of the live webcast to ensure adequate time for anysoftware download that may be necessary.

About Rigel (http://www.rigel.com)

Rigel is a clinical-stage drug development company that discovers anddevelops novel, small-molecule drugs for the treatment ofinflammatory/autoimmune diseases and cancer, as well as viral and metabolicdiseases. Our pioneering research focuses on intracellular signaling pathwaysand related targets that are critical to disease mechanisms. Rigel'sproductivity has resulted in strategic collaborations with largepharmaceutical partners to develop and market our product candidates. Rigelhas product development programs in inflammatory/autoimmune diseases such asrheumatoid arthritis, thrombocytopenia and asthma, as well as in cancer.

Contact: Ryan Maynard

Phone: 650.624.1284

Email: [email protected]

SOURCE Rigel Pharmaceuticals, Inc.

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