NEW YORK, May 18 Reportlinker.com announces that a new market research report is available in its catalogue:
Global Melanoma Therapeutics industry
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This report analyzes the worldwide markets for Melanoma Therapeutics in US$ Million. The report provides separate comprehensive analytics for US, and Rest of World. Annual estimates and forecasts are provided for each region for the period 2007 through 2015. Also, a six-year historic analysis is provided for these markets. The report profiles 73 companies including many key and niche players such as Abraxis BioScience, Inc., Astellas Pharma US, Inc., Antigenics Inc., AVAX Technologies, Inc., BioVex, Inc., GenVec, Inc., GlaxoSmithKline Plc., Medarex Inc., Merck KGAA, Oxford Biomedica Plc, Pfizer, Inc., Progen Pharmaceuticals Limited, and Vical Inc. Market data and analytics are derived from primary and secondary research. Company profiles are mostly extracted from URL research and reported select online sources.
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MELANOMA THERAPEUTICS MCP-6303
A GLOBAL STRATEGIC BUSINESS REPORT
CONTENTS
I. INTRODUCTION, METHODOLOGY & PRODUCT DEFINITIONS
Study Reliability and Reporting Limitations I-1
Disclaimers I-2
Data Interpretation & Reporting Level I-3
Quantitative Techniques & Analytics I-3
Product Definitions and Scope of Study I-3
II. EXECUTIVE SUMMARY
1. MARKET OVERVIEW II-1
Melanoma Incidence Surging at Significant Rate II-1
Current Standard Treatment for Melanoma II-1
High Unmet Need, and Challenges Abound II-1
Recommencement of Discontinued Trials Provides a Ray a Hope! II-2
Cancer Vaccines: Potentially a Future Aid for Melanoma Treatment II-2
How Does Cancer Vaccines Works? II-3
Whole Cell Vaccines for Melanoma II-3
Melanoma Therapeutics Market: Current & Future Analysis II-3
2. MELANOMA PIPELINE - AN OVERVIEW II-4
Research for Novel Drug Therapies Rampant Worldwide II-4
Selected Products and Targets for Melanoma Treatment Under
Phase III Clinical Trials (As of 2008) II-4
Selected Products and Targets for Melanoma Treatment Under
Phase II Clinical Trials (As of 2008) II-5
Selected Products and Targets for Melanoma Treatment Under
Phase I and Pre-Clinical Trials (As of 2008) II-7
Major Drugs Under Investigations for Metastatic Melanoma
Treatment (As of 2008) II-8
What Does the Future Hold for Melanoma in Vaccines Space? II-8
Pipeline Analysis of Melanoma Vaccines II-8
Select Companies with Melanoma Vaccines under Phase III
Clinical Trials II-8
Select Companies with Melanoma Vaccines under Phase II
Clinical Trials II-9
Select Companies with Melanoma Vaccines under Phase I
Clinical Trials II-9
3. MELANOMA: THE DISEASE AND TREATMENT II-10
What is Melanoma? II-10
Melanoma of Skin: A Grave form of Skin Cancer II-10
Melanoma Vis-à-vis Other Skin Cancers II-10
Types of Melanoma II-11
Risk Factors for Melanoma II-11
Indoor Tanning Devices Hold Potential for Causing Skin Cancer II-11
Fair Skinned People: At Greater Risk II-12
Prevention of Melanoma II-12
How Is Melanoma Detected? II-12
Ugly Duckling Sign - A New Approach for Melanoma Detection II-12
Diagnosis of Melanoma II-13
Skin Biopsy, an Initial Step II-13
Fine Needle Aspirate (FNA) II-13
Shave Biopsy II-13
Punch Biopsy II-13
Incisional Biopsy II-13
Excisional Biopsy II-13
Process After Biopsy: A Review II-13
Analysis of Lymph Nodes Status, A Second Step II-14
Lactate Dehydrogenase Tests for Metastases Melanoma II-14
Prognosis of the Disease II-14
Melanoma Staging: Crucial for Treatment II-15
Melanoma Treatment: An Overview II-15
Surgical Excision of Melanoma II-16
Sentinel Lymph Node Biopsy II-16
Standard Treatment, Post Surgery II-16
Surgical Adjuvant Treatment II-17
Standard Excision for Lentigo Maligna II-17
Surgical Treatment of Metastatic Melanoma II-17
Stereotactic Radiosurgery For Brain Metastases Melanoma II-18
Chemotherapy for Melanoma II-18
Side Effects II-18
Chemotherapeutic Regional Perfusion II-19
Immunotherapy for Melanoma II-19
Biochemotherapy: Chemo Plus Biotherapy II-19
Radiation Therapy II-20
Vaccine Immunotherapy II-20
Other Treatments II-20
4. RESEARCH FINDINGS II-21
Vitamin D May Prevent Severe Melanoma Lesions II-21
Stress Accelerates Growth Of Melanoma Lesions II-21
Interaction Between Akt3 and (V600E)B-Raf Proteins in a Mole,
Leads to Melanoma II-21
5. RESEARCH & DEVELOPMENT II-22
Synta Obtains FDA Approval to Resume Development of Elesclomol II-22
Nexavar Fails in Late Stage Melanoma Trial II-22
Biovex Commences Phase III Clinical Trial of Oncovexgm-CSF II-22
Medarex and Bristol Myers Squibb Announces Enhanced Survival
Rate through Ipilimumab II-22
A Pain-Less Melanoma Test, Under Evaluation II-23
Encouraging Phase III Clinical Trials of a Melanoma Vaccine II-23
Plexxikon Announces Phase I Results of PLX4032" II-23
Provectus Treats Metastatic Melanoma Patients Under Phase II
Clinical Study with PV-10 II-24
GENOMEL Project Investigates Environmental/ Genetic Risk
Factors for Melanoma II-24
Antigenics Announces Results of a Phase III Trial of Oncophage
(vitespen) Vaccine II-25
CuraGen Advances Phase II Clinical Trial of "CR011-vcMMAE" II-25
Inovio Evaluates a Combination of Plasmid IL-12 and
Electroporation Technology for the Treatment of Metastatic
Melanoma II-25
6. RECENT INDUSTRY ACTIVITY II-27
Pfizer Collaborates with Debiopharm II-27
PharmaSynth Licenses Muparfostat to Global TransBiotech II-27
Celldex Therapeutics Acquires CuraGen II-27
Bristol-Myers Squibb Acquires Medarex II-28
Cephalon Acquires Outstanding Shares of Arana Therapeutics II-28
ImmunoVaccine Technologies Inks Agreement with Scancell II-29
Vical Inks Agreement with Abic for Allovectin-7 Immunotherapeutic II-29
Immunomedics Collaborates with Alexis Biotech II-29
NeoGenomics Signs Strategic Supply Deal with Abbott II-30
ErgoMed Collaborates with Genzyme II-30
PDS Biotechnology and Merck Eprova Sign CLA II-30
FDA Oncologic Drug Advisory Committee Recommends for Approval,
PEGINTRON® for Melanoma Treatment II-31
Takeda Acquires IDM Pharma II-31
Abraxis BioScience Receives FDA's Orphan Drug Status for Abraxane II-31
Progen Pharmaceuticals Spins-Off its Manufacturing Business II-32
Eli Lilly and Company Acquires SGX Pharmaceuticals II-32
GlaxoSmithKline and Synta Pharmaceutical Obtains the Orphan
Drug Status from the US FDA, for Elesclomol II-32
Vical Inks Binding LOI with EIP II-32
GammaCan Signs Supply Deal with Bio Products Laboratory II-33
Medarex and Bristol Myers Squibb Delays Submission of BLA, for
Ipilimumab II-33
Pfizer Discontinues Phase 3 Clinical Trials of Tremelimumab,
in Advanced Melanoma Patients II-34
Alnylam Pharmaceuticals Collaborates with University of
California to Evaluate an RNAi Therapeutic for Metastatic
Uveal Melanoma Treatment II-34
GenVec and Cobra Ink Manufacturing Agreement II-34
SciClone Pharmaceuticals Sings a Deal with FDA for Thymalfasin II-35
Abraxis BioScience, NCCN, and AstraZeneca Collaborates For
Assessment of Abraxane, the Anti-Cancer Drug II-35
Oxford BioMedica Acquires Oxxon Therapeutics II-36
7. FOCUS ON SELECT GLOBAL PLAYERS II-37
Abraxis BioScience, Inc. (USA) II-37
Astellas Pharma US, Inc. (USA) II-37
Antigenics Inc. (USA) II-37
AVAX Technologies, Inc. (USA) II-38
BioVex, Inc. (USA) II-38
GenVec, Inc. (USA) II-39
GlaxoSmithKline Plc. (UK) II-39
Medarex Inc. (USA) II-40
Merck KGAA (Germany) II-40
Oxford Biomedica Plc. (UK) II-40
Pfizer, Inc. (USA) II-41
Progen Pharmaceuticals Limited (Australia) II-41
Vical Inc. (USA) II-42
8. GLOBAL MARKET PERSPECTIVE II-43
Table 1: World Recent Past, Current & Future Analysis for
Melanoma Therapeutics Market by Geographic Region - US, and
Rest of World Markets Independently Analyzed by Annual Sales
Figures in US$ Million for the Years 2007 through 2015
(includes corresponding Graph/Chart) II-43
Table 2: World Historic Review for Melanoma Therapeutics
Market by Geographic Region - US, and Rest of World Markets
Independently Analyzed by Annual Sales Figures in US$ Million
for the Years 2001 through 2006 (includes corresponding
Graph/Chart) II-44
Table 3: World 15-Year Perspective for Melanoma Therapeutics
Market by Geographic Region - Percentage Breakdown of Sales
for the US, and Rest of World Markets for the Years 2003, 2009
& 2015 II-44
III. MARKET
1. THE UNITED STATES III-1
A.Market Analysis III-1
Increasing Incidence of Melanoma Fuels Growth III-1
Table 4: Melanoma Incidence in the US by Gender: 2008 III-1
Table 5: Cancer Incidence in Males by Cancer Type:
Percentage Share Breakdown in 2008 (includes corresponding
Graph/Chart) III-1
Table 6: Cancer Incidence in Females by Cancer Type:
Percentage Share Breakdown in 2008 (includes corresponding
Graph/Chart) III-2
Surging Mortality, Demands Novel Therapeutics for Melanoma III-2
Table 7: Melanoma Mortality in the US by Gender: 2005 &
2008 (includes corresponding Graph/Chart) III-2
Table 8: Five-Year Survival Rate for Patients with Melanoma
of Skin in the US (1996-2003): Percentage Share Breakdown
by Diagnosis Stage (includes corresponding Graph/Chart) III-3
Fair-Skinned and Light Hair Whites at High Risk III-3
Table 9: Five-Year Survival Rate for Patients with Melanoma
of Skin in the US (1996-2003): Percentage Share Breakdown
by Race (includes corresponding Graph/Chart) III-3
US Melanoma Fact Sheet: A Recapitulation III-4
Major Players III-4
Strategic Corporate Developments III-8
B.Market Analytics III-15
Table 10: US Recent Past, Current & Future Analysis for
Melanoma Therapeutics Market with Annual Sales Figures in
US$ Million for Years 2007 through 2015 (includes
corresponding Graph/Chart) III-15
Table 11: US Historic Review for Melanoma Therapeutics
Market with Annual Sales Figures in US$ Million for Years
2001 through 2006 (includes corresponding Graph/Chart) III-15
2. REST OF WORLD III-16
A.Market Analysis III-16
Select Regional Markets Under Review III-16
Australia III-16
World's Leading Region with Highest Skin Cancer Incidence III-16
Table 12: Melanoma Incidence Rate in Australia by Age
Group: 2008 (2008) (includes corresponding Graph/Chart) III-16
Table 13: Melanoma Incidence Rate in Australian Males by
Age Group: 2008 (includes corresponding Graph/Chart) III-16
Table 14: Melanoma Incidence Rate in Australian Females
by Age Group: 2008 (includes corresponding Graph/Chart) III-17
Other Key Facts on Melanoma Incidence in Australia III-17
The United Kingdom III-17
Young Women in UK Becoming Increasing Victims of Melanoma III-17
Table 15: Newly Diagnosed Cases of Melanoma of Skin in
the UK (2003-2005): Breakdown by Select Regions, and
Gender (includes corresponding Graph/Chart) III-18
Table 16: Mortality Due to Melanoma of Skin in the UK
(2003-2005): Breakdown by Select Regions, and Gender
(includes corresponding Graph/Chart) III-18
Major Players III-18
Strategic Corporate Developments III-20
B.Market Analytics III-24
Table 17: Rest of World Recent Past, Current & Future
Analysis for Melanoma Therapeutics Market with Annual Sales
Figures in US$ Million for Years 2007 through 2015 (includes
corresponding Graph/Chart) III-24
Table 18: Rest of World Historic Analysis for Melanoma
Therapeutics Market with Annual Sales Figures in US$ Million
for Years 2001 through 2006 (includes corresponding
Graph/Chart) III-24
IV. COMPETITIVE LANDSCAPE
Total Companies Profiled: 73 (including Divisions/Subsidiaries - 80)
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Region/Country Players
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The United States 59
Canada 2
Japan 1
Europe 13
France 1
Germany 5
The United Kingdom 4
Rest of Europe 3
Asia-Pacific (Excluding Japan) 3
Middle East 2
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