HILDEN, Germany and GERMANTOWN, Md., June 3, 2017 /PRNewswire/
The agreement involves rights to genetic biomarkers to assess microsatellite instability (MSI) and mismatch repair (MMR) in all sample and cell types, and will enable QIAGEN – subject to its exercising certain option rights – to commercialize molecular testing solutions using next-generation sequencing to assess MSI and MMR status. Levels of MSI and MMR, along with tumor mutation burden (TMB), are important in identifying cancer patients who could benefit from certain types of I-O therapies, which offer a novel way to treat cancer by using drugs to target the body's immune system to help fight cancer.
QIAGEN reached this agreement prior to the U.S. Food and Drug Administration's (FDA) approving in May 2017 an I-O therapy to treat advanced solid tumors with MSI and MMR deficiencies, marking the first time that the FDA has cleared a cancer drug for use not tied to the site of a tumor. The Johns Hopkins University has been at the forefront of research in linking MMR defects to cancer.
Click here for full press release
To view the original version on PR Newswire, visit:http://www.prnewswire.com/news-releases/qiagen-expands-biomarker-content-portfolio-to-support-greater-use-of-molecular-diagnostics-for-immuno-oncology-therapies-300468295.html
Subscribe to our Free Newsletters!
Erythropoietin is a hormone secreted by kidneys in response to low oxygen levels in tissues ...
Local anesthesia is a type of anesthesia generally used to block pain sensation only in a specific ...
Sea food allergy is the adverse response of the body''s immune system to the proteins present in ...View All