AMSTERDAM, November 14, 2016 /PRNewswire/ --
Pharmaceutical companies are getting more sophisticatedin the way they get products to poor people and are addressing global health priorities. However, good practice is limited to a narrow range of products and countries. Opportunities to expand efforts are yet to be realised.
The 2016 Access to Medicine Index, published Monday, ranks the top 20 pharmaceutical companies on their efforts to improve access to medicine in low- and middle-income countries. It found that GSK, which leads the Index for the fifth time, performs best at matching its access activities with particular needs within the access-to-medicine agenda.
GSK is joined at the top of the Index by a closely packed group: Johnson & Johnson, Novartis and Merck KGaA. The pharmaceutical industry is extremely diverse, which is reflected in the way each company approaches access to medicine. However, the four leading companies share some distinguishing characteristics. They have the most mature access programmes, with well-organised access strategies that support business development in emerging markets, where the need for access to medicine is high. They also show the most evidence of addressing independently identified high-priority needs.
The 2016 Index has assessed the extent to which a company's access operations are needs-oriented: where actions match specific priorities identified by, for instance, countries, the global health community or the Index. In this regard, the Index reveals uneven performance.
The companies have 850 products on the market for the 51 most burdensome diseases in low- and middle-income countries, and are developing another 420. This includes more than 100 products that entered the pipeline since 2014, and 151 with low commercial incentive but which are urgently needed by the poor.
The majority (67%) of the research projects companies have for high-priority, low-incentive products are being conducted in partnerships, the Index finds.
"We see evidence that collaborative R&D models are engaging the industry in developing urgently needed medicines they would not otherwise be considering because there is not enough commercial incentive," said Jayasree K. Iyer, Executive Director of the Access to Medicine Foundation. "The partnership approach is working."
Progress in making more medicines more available is also seen in the ways companies are handling patents and the extent to which they allow other manufacturers to make generic versions of their products.
Since 2014, seven companies have published or expanded pledges to waive or abandon patent rights for certain products in certain regions. More HIV/AIDS products are covered by voluntary licences, which apply in more countries than before. For the first time, they are being used to expand access to medicine for a disease other than HIV/AIDS - hepatitis C. Globally, between 130-150 million people have chronic hepatitis C infection.
Products can only be made available in a country once they have been registered there. The Index finds that companies apply to register their newest products in only 25% of countries the Index identifies as having highest priority.
Making products more affordable is a cornerstone of increasing access to medicine. The Index finds that pricing schemes that take ability to pay into account are being applied to one-third of relevant products. This has not changed since the last Index two years ago. Only 5 % of products (44 out of 850) have such pricing strategies applied in countries the Index identifies as highest-priority, and that take at least one socio-economic factor into account. Around half these products are from GSK and AstraZeneca.
Other findings include:
The companies that rose most significantly were AstraZeneca and Takeda, which both extensively expanded and updated their access strategies. AstraZeneca climbed eight positions into the top 10 on 7th position. Takeda moved up five places to 15th.
Meanwhile, Novo Nordisk, Roche and Gilead have experienced the most significant drops in ranking, after being outperformed by peers.
"We have been assessing these 20 companies for 10 years now. We know what works, where. There is good practice and where there are mechanisms to incentivise industry engagement, such as patent pooling, collaborative R&D models, multi-stakeholder initiatives and international commitments to certain diseases, we see the industry responding," Iyer said. "Access to medicine is a collective responsibility and all stakeholders -from the industry to governments and the global health community- need to challenge themselves to support the ramping up of these efforts to ensure they are expanded to more products in more countries so that pharmaceutical products reach the people who need them."
Note to editors:
Media materials: The overall ranking, related data points, graphs and figures (e.g., from the Key Findings) in the report are available upon request.
About the Access to Medicine Index: The Access to Medicine Index analyses the top 20 research-based pharmaceutical companies with products for high-burden diseases in low- and middle-income countries. The Index ranks these companies on their efforts to improve access to medicine in seven areas of corporate behaviour. It identifies best practices, highlights where progress is being made, and uncovers where critical action is still required. It is published every two years by the Access to Medicine Foundation, an independent non-profit organisation funded by the UK Government (UK AID), the Dutch Ministry of Foreign Affairs and the Bill & Melinda Gates Foundation.
For more information, contact: Suzanne Wolf Tel: +31-6-29-40-40-90 or +31-23-53-39-187 Email: [email protected] Website: http://www.atmindex.org
SOURCE Access to Medicine Index
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