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PLC Systems Updates Common Stock Listing Status

Thursday, November 13, 2008 General News J E 4
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FRANKLIN, Mass., Nov. 12 PLC Systems Inc.(Pink Sheets: PLCSF), a company focused on innovative cardiac and vascularmedical device-based technologies, today stated that, following the delistingof its common stock from NYSE Alternext (formerly known as the American StockExchange) on Monday, November 10, 2008, the company is working to secure theintended transfer of its common stock listing to the OTCBB. Until that listingis accomplished, the company's common stock is trading on the Pink Sheets, andinformation can be found at www.pinksheets.com under the symbol "PLCSF". Whenthe transfer to OTCBB is completed, the company will announce the new tradingsymbol on that market.

About PLC Systems Inc.

PLC Systems Inc. is a medical technology company specializing ininnovative technologies for the cardiac and vascular markets.

PLC's newest product, RenalGuard, is approved for sale in the EU as ageneral fluid balancing device. The RenalGuard System consists of a unique,proprietary, closed loop, software-controlled console and accompanying single-use sets that can be used by physicians and nurses to balance patient fluidlevels during a variety of medical procedures. With its automated matchedfluid replacement capability, RenalGuard is intended to minimize the risk topatients of over- or under-hydration while also largely eliminating what canbe an intensive and time consuming manual fluid balancing task for physiciansand nurses.

Headquartered in Franklin, Massachusetts, PLC pioneered the CO2 HeartLaser System, which cardiac surgeons use to perform CO2 transmyocardialrevascularization (TMR) to alleviate symptoms of severe angina. CO2 TMR offersa treatment option for angina patients who suffer from severe coronary arterydisease. The CO2 Heart Laser is the world's first TMR angina relief devicecleared for commercial distribution by both the U.S. Food and DrugAdministration and Japanese Ministry of Health, Labor and Welfare, and toobtain a CE Mark for distribution within the EU.

Additional company information can be found at www.plcmed.com.

This press release contains "forward-looking" statements. For thispurpose, any statements contained in this press release that relate toprospective events or developments are deemed to be forward-lookingstatements. Words such as "believes," "anticipates," "plans," "expects,""will" and similar expressions are intended to identify forward-lookingstatements. Our statements of our objectives are also forward-lookingstatements. While we may elect to update forward-looking statements in thefuture, we specifically disclaim any obligation to do so, even if ourestimates change, and you should not rely on these forward-looking statementsas representing our views as of any date subsequent to the date of this pressrelease. Actual results could differ materially from those indicated by suchforward-looking statements as a result of a variety of important factors,including that our stock may not be accepted for trading on the OTCBB, andadditional risk factors described in our Quarterly Report on Form 10-Q for thequarter ended June 30, 2008, and our other SEC reports.

PLC Systems, PLC Medical Systems, PLC and CO2 Heart Laser, and RenalGuardare trademarks of PLC Systems Inc.Contact: Mary T. Conway Conway Communications 617-244-9682 mtconway@att.net

SOURCE PLC Systems Inc.
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