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Milestone Scientific Expands Global Distribution Network

Wednesday, June 4, 2008 General News J E 4
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LIVINGSTON, N.J., June 3 Milestone ScientificInc. (OTC Bulletin Board: MLSS), the recognized leader in advanced injectiontechnologies, today announced that Istrodent Pty Ltd AB, a leading SouthAfrican distributor of dental products to professional dental practitioners,has been granted exclusive rights to market, distribute and sell Milestone'saward-winning STA(TM) System throughout Southern Africa.

With its headquarters in Johannesburg and operations in Cape Town andDurban, Istrodent (http://www.istrodent.com) is one of the largest dentaldistributors and manufacturers in Southern Africa serving the needs ofdentists in South Africa, Lesotho, Swaziland, Zambia, Namibia, Botswana,Mozambique, Angola, Malawi and Kenya. Recognized as the region's leadingsource for dental innovations and technical solutions, Istrodent representsnumerous major brands and manufacturers in the global dental arena. Milestonejoins other world leading suppliers that rely on Istrodent to reach the SouthAfrican dental community, including KaVo-Germany, Soredex-Finland,Villa-Italy, AFP Imaging- USA, DCI-USA, SDS-USA, Tuttnauer-Israel, GCMaterial-Japan, OSADA Equipmen-Japan, KOMET-Germany, CATANI and MEDESY-Italy,among many others.

In addition, Istrodent has earned distinction throughout the SouthernAfrican region for building mobile dental clinics, a market it has dominatedsince 1994. Through Istrodent's successful collaborations withColgate/Transnet on the Phelopepa Healthcare Train and with the South AfricanGovernment, there are at least 100 mobile dental clinics currently inoperation within the South African borders.

According to Joe Martin, Chief Executive Officer of Milestone, "Workingwith Istrodent, Milestone achieved notable market penetration of the SouthAfrican dental market for The Wand(R). In fact, Istrodent has historicallyproven to be one of our strongest marketing allies outside of the UnitedStates. Consequently, we are pleased that we have the opportunity to onceagain leverage Istrodent's market leadership to introduce the STA System."

The state-of-the-art STA System is Milestone's latest achievement incomputer-controlled local anesthesia delivery (CCLAD) that makes the injectionprocess more comfortable for both dentists and patients. Marketed for use bydental practitioners to painlessly administer all dental injections, the STASystem is uniquely capable of administering "Single Tooth Anesthesia" into thePeridontal Intraligamentary (PDL) space, something never before possible usingconventional techniques. In 2007, Milestone was granted CE Mark approval forthe STA System, paving the way to begin marketing the instrument to dentistsin African countries and other countries around the world that recognize theCE Mark approval process.

About Milestone Scientific Inc.

Headquartered in Livingston, New Jersey, Milestone Scientific is engagedin pioneering proprietary, highly innovative technological solutions for themedical and dental markets. Central to the Company's IP platform and productdevelopment strategy is its patented CompuFlo(R) technology for the improvedand painless delivery of local anesthetic. Specifically, CompuFlo is acomputer-controlled, pressure sensitive infusion, perfusion, suffusion andaspiration technology, which provides real-time readouts of pressures, fluiddensities and flow rates, enabling the advanced delivery and removal of a widearray of fluids. The STA(TM) (Single Tooth Anesthesia) Systemcomputer-controlled local anesthesia delivery system which uses thistechnology provides dentists with audible and visual signals as to in-tissuepressure. Milestone's existing painless injection systems are currently soldin 25 countries. For more information on these and other innovative Milestoneproducts, please visit the Company's web site found at http://www.milesci.com.

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