MicroCHIPS CEO Named in Popular Science's 'Seventh Annual Brilliant 10'

Wednesday, October 15, 2008 General News J E 4
BEDFORD, Mass., Oct. 14 John Santini, Jr., PhD, CEO ofMicroCHIPS, Inc., is named by Popular Science magazine as a member of the 2008class of "young geniuses shaping the future of science." In the history ofthis annual list, Dr. Santini is the only honoree who is also a successfullife sciences entrepreneur running his own commercial venture. His company,MicroCHIPS, is pioneering intelligent medical devices for drug delivery andbiochemical sensing.

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Dr. Santini began developing the microreservoir technologies that are atthe core of his company's products as a doctoral student in the labs of Dr.Robert Langer and Dr. Michael Cima at the Massachusetts Institute ofTechnology. He founded MicroCHIPS with Drs. Langer and Cima as well as TerryMcGuire of Polaris Venture Partners in 1999. MicroCHIPS is developingnext-generation biosensing and drug delivery devices to increase therapeuticcontrol and effectiveness for people with diabetes, osteoporosis and otherdebilitating diseases.

"I am honored to be a part of a list of such accomplished individuals,"said Dr. Santini, President and CEO, MicroCHIPS. "It is exciting to see ourunique technologies take shape as products that can transform how cliniciansand patients manage serious, chronic conditions."

"It is gratifying to see how John is helping to move microreservoirtechnology from 'bench to the bedside,'" said Robert Langer, ScD., InstituteProfessor at MIT. "He is working to realize our vision of innovativelong-term devices that can deliver drugs and sense chemicals with exquisitecontrol."

Under Dr. Santini's leadership, MicroCHIPS plans to begin clinical work in2009 for its lead products, a long-term continuous glucose monitor fordiabetes, and a drug delivery device for osteoporosis.

About MicroCHIPS

MicroCHIPS, Inc. is pioneering intelligent implanted devices designed toimprove the health of millions of people with chronic conditions that requirecareful monitoring and precise therapy. Based on proprietary microreservoirtechnology first developed at MIT, MicroCHIPS' platform incorporates long-termimplant technologies and wireless communications, as well as expertise inprotein and peptide formulation for challenging delivery conditions.MicroCHIPS' technologies are designed to transform electromechanical medicaldevices into highly tuned biochemical sensing and therapy systems.

About Popular Science's Annual "Brilliant 10"

For the past six years, Popular Science has published an article called"Popular Science's Brilliant 10," in which the magazine profiles ten youngscientists doing work that is pushing their field to the next level. To choosethe ten recipients the editors contact hundreds of individuals, includingheads of departments at universities around the country, professionalassociations and award-granting institutions.



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