Advertisement
Replikins are peptides, specified in virus genomes, which increase inconcentration signaling rapid replication before virus outbreaks. This is thefirst report that cyclic increases in virus replikin concentration, eachapparently building on the last, can be a mechanism of virus expansion into aterritory.
Advertisement
In the present study, virus ReplikinCount(TM) determined byFluForecast(TM) software was correlated with CDC epidemiological data on thenumber of human cases per year. Discrete cycles were distinguished within, andcorrelated between, virus chemistry and host morbidity. The mosquito-borneWest Nile virus, which apparently incubates between seasons, has been found toincrease its concentration of Replikins before the next annual step in thecycle of expansion.
This demonstration of replikin cycles represents further "proof ofprinciple" on the relationship of replikins to virus epidemics, and a newmeans of discerning the course of an epidemic. Previously, increases in theReplikinCount of the Replikins Peak Gene were found to precede and to predictoutbreaks and lethality of two other viruses, influenza H5N1 and TauraSyndrome Virus, in two hosts, human and shrimp respectively. The conservationof specific replikin structures over many years, the detection of newreplikins, and the chemical synthesis of replikin vaccines in 7 days,demonstrated for H5N1 and Taura Syndrome viruses, have now also beendemonstrated for West Nile Virus.
For further information, Google "replikins," and see U.S. Patent Officepublications.
This release was issued through eReleases(TM). For more information,visit http://www.ereleases.com.Contact: Replikins Ltd., 38 The Fenway, Boston MA 02215 email: [email protected] Tel: 646-320-5910 http://www.Replikins.com
SOURCE Replikins Ltd.
