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"The submission of this IND represents a critical milestone in the therapeutic development of the pyrimidinedione class of molecules as potential new HIV drugs and an important success in the strategic drug development initiatives between ImQuest and Samjin Pharmaceutical Co. Ltd of Seoul, KOREA," said Dr. Robert W. Buckheit, Jr., Executive Vice President and Chief Scientific Officer of ImQuest Life Sciences. "We believe that IQP-0410 will be a new and novel addition to the armamentarium of HIV drugs available and provide HIV-infected individuals with a safe and effective alternative to current therapies."
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ImQuest and Samjin have continued their strategic efforts to develop additional pyrimidinediones as next generation NNRTIs with an enhanced genetic barrier to resistance as well as efforts to develop a topical microbicide to prevent the sexual transmission of HIV. Additionally, ImQuest's development of Samjin's piperazine anti-tumor agents for the treatment of both solid and hematopoietic tumors has progressed to IND-enabling toxicology evaluations. These products are expected to enter human clinical trials in late 2009 and 2010.
ImQuest Life Sciences (www.imquestls.com) in Frederick, Maryland specializes in the preclinical and clinical development of novel compounds for the treatment of infectious disease and cancer. ImQuest BioSciences (www.imquest.com) is a leading provider of anti-infective and anti-cancer drug and vaccine development services to the biotechnology and pharmaceutical industry. Established in 1968, Samjin Pharmaceutical Co. (www.samjinpharm.co.kr/eng) is dedicated to the manufacture, distribution and marketing of novel pharmaceuticals resulting in numerous international patents covering antiviral, anticancer, and metabolic candidate compounds. The company has recently expanded their scope to include stem cell research and the active pursuit of diabetic treatments.
SOURCE ImQuest Life Sciences, Inc.