Gates Foundation Now Accepting Proposals for Grand Challenges Explorations

Tuesday, April 1, 2008 General News J E 4
SEATTLE, March 31 The Bill & Melinda Gates Foundationannounced today that it is now accepting grant proposals for the first roundof Grand Challenges Explorations, a US$100 million initiative to encouragebold and unconventional global health solutions. Proposals will be acceptedonline at through May 30, 2008; applicantsmust register their intent to submit a proposal by May 15, 2008.

The initiative, the first of its kind for the foundation, uses an agile,accelerated grant-making process. Applications are two pages, and preliminarydata about the proposed research are not required. One of the primaryobjectives of Grand Challenges Explorations is to involve scientists aroundthe world who don't typically work in global health -- this includesinnovators in Africa, Asia, and other parts of the developing world; thosefrom complementary disciplines and in the private sector; and younginvestigators.

The first four topic areas for which proposals will be accepted throughthe Grand Challenges Explorations initiative are:

The foundation and an independent group of reviewers will select the mostinnovative proposals, and grants will be awarded within approximately threemonths from the proposal submission deadline. Initial grants will be $100,000each. Projects showing success will have the opportunity to receiveadditional funding of $1 million or more.

Full descriptions of these topic areas and application instructions areavailable at

Guided by the belief that every life has equal value, the Bill & MelindaGates Foundation works to help all people lead healthy, productive lives. Indeveloping countries, it focuses on improving people's health and giving themthe chance to lift themselves out of hunger and extreme poverty. In theUnited States, it seeks to ensure that all people -- especially those with thefewest resources -- have access to the opportunities they need to succeed inschool and life. Based in Seattle, the foundation is led by CEO PattyStonesifer and co-chair William H. Gates Sr., under the direction of Bill andMelinda Gates and Warren Buffett.-- Creating new ways to protect against infectious diseases, including alternatives to traditional vaccination. -- Creating new drugs and delivery systems to limit the emergence of resistance from developing in the disease-causing agent. -- Creating new ways to prevent or cure HIV infection that fall outside current research on vaccines, antiretroviral drugs, and other biomedical and behavior-change strategies. -- Exploring the basis for latency in TB, with the goal of discovering new ways to identify and eliminate latent infection, and break the cycle of TB transmission.

SOURCE Bill & Melinda Gates Foundation


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