For the Treatment of Osteoporosis, a Drug's Effect on Reduction of New Hip Fractures Is the Attribute that Most Influences Surveyed PCPs' Prescribing Decisions

Friday, March 5, 2010 General News
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WALTHAM, Mass., March 4 Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that a drug's effect on reduction of new hip fractures is the attribute that most influences U.S. and European surveyed primary care physicians' (PCPs') prescribing decisions in osteoporosis. Clinical data and the opinions of interviewed thought leaders indicate Eli Lilly's Forteo (in Europe the brand name is Forsteo) has advantages over patient-share leader alendronate (Merck's Fosamax, Teijin's Bonalon, generics) on this attribute.

The new report entitled Osteoporosis: Prolia Fails to Meet Physicians' Expectations but Retains Blockbuster Potential also finds that Forteo will remain Decision Resources' proprietary clinical gold standard through 2018 for the treatment of osteoporosis. While some drugs in development hold promise, such as Amgen/GlaxoSmithKline's Prolia, most have less favorable efficacy, safety and tolerability attributes compared with Forteo.

"Amgen/GlaxoSmithKline's first-in-class biologic Prolia has not demonstrated sufficient efficacy to surmount Forteo as our clinical gold standard. Physicians continue to seek improved fracture prevention and although Prolia's twice yearly injections offer greater convenience than Forteo, which requires daily injections, Prolia doesn't demonstrate superiority in efficacy," stated Decision Resources Analyst Matthew Scutcher, Ph.D. "Although Prolia will still achieve blockbuster status in the osteoporosis drug market, its uptake will be limited by competition from Forteo and other currently marketed therapies."

About the Report

Osteoporosis: Prolia Fails to Meet Physicians' Expectations but Retains Blockbuster Potential is a DecisionBase 2010 report. DecisionBase 2010 is a decision-support tool that provides in-depth analysis of unmet need, physician expectations of new therapies and commercial dynamics to help pharmaceutical companies optimize their investments in drug development.

About Decision Resources

Decision Resources ( is a world leader in market research publications, advisory services and consulting designed to help clients shape strategy, allocate resources and master their chosen markets. Decision Resources is a Decision Resources, Inc. company.

About Decision Resources, Inc.

Decision Resources, Inc. is a cohesive portfolio of companies that offers best-in-class, high-value information and insights on important sectors of the healthcare industry. Clients rely on this analysis and data to make informed decisions. Please visit Decision Resources, Inc. at

All company, brand or product names contained in this document may be trademarks or registered trademarks of their respective holders.

For more information, contact: Decision Resources Christopher Comfort 781-296-2597

SOURCE Decision Resources

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