First-in-class BRCA-positive Ovarian Cancer Medicine Lynparza® (olaparib) Receives Positive pan-Canadian Oncology Drug Review (pCODR) Recommendation for Provincial Reimbursement

Thursday, September 21, 2017 General News
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References_________________________________1 Lynparza® (olaparib) Product Monograph. Accessed August 30, 2017. Available at: https://www.astrazeneca.ca/content/dam/az-ca/downloads/productinformation/lynparza-product-monograph-en.pdf 2 Product Monograph, op. cit. 3 Pujade-Lauraine, J.A., et al. Olaparib tablets as maintenance therapy in patients with platinum-sensitive, relapsed ovarian cancer and a BRCA1/2 mutation (SOLO2/ENGOT-Ov21): a double-blind, randomised, placebo-controlled, phase 3 trial. Lancet Oncol. 2017. Accessed August 30, 2017. Available at: http://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(17)30469-2/abstract 4 Ibid.5 Ovarian Cancer Canada. Hereditary One-Pager. Page 2. Accessed September 27, 2016. On file.6 AstraZeneca Feedback on pERC Initial Recommendation. Lynparza (olaparib) for PSR BRCAm Ovarian Cancer, on file. 7 Ovarian cancer: Survival statistics. Accessed August 30, 2017. Available at: http://www.statcan.gc.ca/pub/82-624-x/2015001/article/14212-eng.htm#a1 8 Ovarian Cancer Canada. Hereditary One-Pager, op. cit.9 Litton, J.K. et al. Earlier age of onset of BRCA mutation-related cancers in subsequent generations. Cancer. 2012 Jan 15;118(2):321-5.



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