European Hematology Association: Delayed Exposure to Common Infections Causes Acute Leukemia of Childhood

Friday, June 23, 2017 Child Health News
Email Print This Page Comment bookmark
Font : A-A+

MADRID, June 23, 2017 /PRNewswire/ --

Acute leukemia is the most common cancer in childhood and the incidence is

increasing especially in socio economic advanced countries. Infection as a trigger of leukemia development in children has been controversially discussed since decades and leukemia occurrence in time-space cluster supports this hypothesis. However experimental
evidence, which proves the connection of exposure to infection and childhood leukemia is rare. We and colleagues have established and characterized two genetically modified mouse models representing classical subtypes of childhood leukemia (Pax5+/- and TEL-AML1). The mice develop acute lymphoblastic leukemia only after exposure to a common infection environment and represent a similar phenotype as compared to acute lymphoblastic leukemia in childhood. This work offers for the first time novel insight into the role of infection in leukemia development and offers novel approaches for leukemia prevention.

     (Logo: http://mma.prnewswire.com/media/524821/EHA_Logo.jpg )    

Presenter:  Dr Julia Hauer

Affiliation:  Clinic for Pediatric Oncology, Haematology and Clinical Immunology, Düsseldorf, Germany

Topic:  EXPOSURE TO INFECTION TRIGGERS PAX5 AND ETV6-RUNX1 CHILDHOOD BCP-ALL

Abstract S148 will be presented by Julia Hauer on Friday, June 23 15:45 - 17:00 in Hall A.

About the EHA Annual Congress Hematology is a specialty that covers everything to do with blood: its origin in the bone marrow, diseases of blood and their treatments. The latest data on research and developments will be presented. The topics range from stem cell physiology and development, to leukemia, lymphoma, myeloma - diagnosis and treatment; red blood cells -, white blood cells- and platelet disorders; thrombosis and bleeding disorders.

SOURCE European Hematology Association



Post your Comments

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
* Your comment can be maximum of 2500 characters
I agree to the terms and conditions

News A - Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

News Search

Medindia Newsletters

Subscribe to our Free Newsletters!

Terms & Conditions and Privacy Policy.

Find a Doctor

Press Release Category

Press Release Archive

Stay Connected

  • Available on the Android Market
  • Available on the App Store

Facebook