Edison Issues Initiation on Silence Therapeutics (SLN)
LONDON, July 25, 2016 /PRNewswire/ --
Silence Therapeutics is a leading RNA therapeutics development company, with proprietary RNA interference (RNAi) technology (AtuRNAi) and delivery systems (LipoPLEXes). RNAi can be harnessed to silence the expression of any disease-causing protein. The basic rationale is simple: find any gene in the genome that is causing problems and synthesise an RNA molecule to shut down or upregulate the gene as necessary. Silence has an extensive genetic toolkit that addresses the technical challenges of delivery and therefore could offer 'multiple shots at goal', ie a broad range of potential indications. Silence is well funded following a fund-raising of £38.9m in 2015 to progress its early-stage technology.
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We do not assign a fair value to Silence at this stage because its focus is currently on its preclinical pipeline and developing partnerships for its broader IP portfolio. We believe Silence offers one of the broadest ranges of RNA technologies in the sector, which could provide significant upside potential if the company executes its strategy. The company is well-funded following a £38.9m (net) fund-raising in 2015.
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