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Manfred Zierhut, Professor in the Department of Ophthalmology at theUniversity of Tuebingen in Germany, will present preclinical pharmacokineticdata on ESBA105 on Friday, September 12, 2008, at the 7th InternationalSymposium on Uveitis in Constance, Germany. For more information on thesymposium and on Prof. Zierhut's abstract, please visit www.iusg2008.org/.
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Dominik Escher, Ph.D., Chief Executive Officer of ESBATech AG, commented,"The completion of this Phase I study with ESBA105 in ophthalmic indicationsmarks a critical clinical milestone for the company. Recently, ESBATechsecured CHF 23M (USD 22M) in an extended Series B venture financing round.This financing will fund further clinical studies with ESBA105 in ophthalmicindications, as well as build broad franchises in ophthalmology, rheumatologyand respiratory diseases for ESBA105 and other antibody fragments. We lookforward to announcing the results of this Phase I study and future clinicaltrials."
Peter Lichtlen, M.D., Ph.D., Head of Clinical Development at ESBATech AG,commented, "We are encouraged by the safety and pharmacokinetic profile thatESBA105 has demonstrated in this Phase I study and we look forward tocontinuing our progress in the clinical development of this product."
About ESBATech AG
ESBATech AG is a Zurich, Switzerland-based, privately held drug discoveryand development company focused on advancing antibody fragments fortherapeutic applications. The company applies its proprietary, fully humansingle-chain antibody frameworks to generate product candidates againsttargets of clinical relevance. ESBATech is focused on delivering highconcentrations of its therapeutic antibody fragments to the targeted sites, incombination with extremely low systemic load, in order to achieve low risk ofsystemic drug reactions using topical and local delivery.
Current venture investors include SV Life Sciences, Clarus Ventures, HBMBioVentures, HBM BioCapital, Novartis Bioventures, BioMedinvest and VIPartners. For more information about ESBATech, please visit, www.esbatech.com.
SOURCE ESBATech AG