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"In situ laser processing with LEAP has provided us the unique ability topurify rare adherent cell types in an efficient, automated and sterilemanner," said Mark Mercola, Ph.D., Professor and Associate Director, Del E.Webb Neuroscience, Aging and Stem Cell Research Center. "We also believe LEAPcan be a transforming technology in the downstream use of stem cells and theirprogeny as it has clear potential as a sample preparation system for adherentcell types derived from stem cell populations."
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LEAP is an automated live cell analysis and processing system thatcombines high-speed optical imaging (brightfield or fluorescence) andreal-time image analysis with high-speed in situ laser manipulation of cells.Using LEAP, researchers have demonstrated: (i) accelerated functional cloningof cells, including highly-secreting cells for biopharmaceutical manufacturingpurposes, (ii) image-based cell purification of adherent and non-adherent celltypes and (iii) laser-based macromolecule delivery into cells, includingsiRNA, small molecules, proteins and quantum dots.
"Burnham scientists are clearly among the elite in the world of stem cellbiology and we are excited to be working closely with them to exploit LEAP'scapabilities to improve their potential in working with stem cells," statedDr. Fred Koller, Cyntellect's President and CEO. "It is an important and nobleendeavor that we hope and expect will offer some novel and powerful solutionsto the life science and therapeutic markets."
About Burnham Institute for Medical Research
Burnham Institute for Medical Research is dedicated to revealing thefundamental molecular causes of disease and devising the innovative therapiesof tomorrow. Burnham is one of the fastest growing research institutes in thecountry with operations in California and Florida. The Institute ranks amongthe top four institutions nationally for NIH grant funding and among the top25 organizations worldwide for its research impact. Burnham utilizes a unique,collaborative approach to medical research and has established major researchprograms in cancer, neurodegeneration, diabetes, infectious and inflammatoryand childhood diseases. The Institute is known for its world-classcapabilities in stem cell research and drug discovery technologies. Burnham isa nonprofit, public benefit corporation. For more information, please visithttp://www.burnham.org.
About Cyntellect
Cyntellect, Inc. is a life sciences company committed to revolutionizingthe use of living cells in life science research and cellular therapy. TheCompany combines expertise in high-speed cell imaging and laser-basedmanipulation to develop products that enable novel cell imaging, purification,and transfection capabilities to enhance the productivity of laboratoryresearch, recombinant protein production, high-content cellular assays,functional genomics and proteomics, and cell purification, includingprocessing of cells for therapeutic
